In the modern urban context, the "Westward Journey" task force of the Supernatural Crime Investigation Section, led by criminal psychology professor Chen Xuanzang, has assembled Sun Qitian, a trace expert who was exiled from the system, Zhu Gang, a former gold medal undercover reporter, Sha Jing, a retired military forensic doctor, and Bai Long, a descendant of a hacker family, to specialize in detecting supernatural and serial serious cases that cannot be intervened by the regular police system. Each case corresponds to the core of human nature in the original work "Eighty-One Difficulties", from appearance obsession, data hegemony to cult manipulation and capital alienation. In the process of unraveling bizarre crimes, the task force constantly came into contact with the core conspiracy of the "Immortality Society", a secret organization that shrouded the city. This organization attempted to integrate ancient secrets with modern biology and digital technology to achieve eternal consciousness, and Chen Xuanzang's special psychological constitution was the key to the longevity plan. From a temporary alliance of contradictions, the team completes self-salvation and spiritual growth during life and death investigations, and finally faces the ultimate controller behind the Immortality Society, protecting the true nature of human nature and urban order. The book is structured in 81 chapters to complete the spiritual practice of "subduing demons, slaying demons, and seeing the inner demons."