The background of the story is set in Yangzhou City in the 25th year of Wanli Dynasty, where the smell of powder and copper are intertwined. A bizarre "Four Fateful Injustices" occurred on a painting boat. The deaths were in different ways, which attracted the attention of Dali Temple forensic doctor Gu Shen. Behind the scenes is the "Wanjie Tower", a huge organization that controls the salt affairs of Huaihe and Huaihe Rivers. Ten years of blood feud, shadow puppets, poisons and intrigues all come into play. A thrilling crime-solving drama begins in the mist and rain in the south of the Yangtze River.