Medical expert Xiao Qingyin Pharmaceutical was killed in an explosion and transformed into the legitimate daughter of the minister's mansion who was kidnapped into a bandit's den. She unexpectedly cooperated with the poisoned Yong'an Prince Yi Shuihan to escape from trouble, but her scumbag stepmother plotted to marry Yi Shuihan, the "living king of hell" for her sister. Xiao Qingyin relied on her medical skills and wisdom to resolve frame-ups many times, exposing her stepmother Yao's conspiracy to poison her biological mother and murder the eldest princess. She also discovered that Yi Shuihan was the "Mrs. Yazhai" whom she had met before. In the end, the two teamed up to bring down the prince and the villain, and found his biological mother. Xiao Qingyin even married Yi Shuihan as the "groom" and gained happiness.