In order to find out the truth about her biological mother's untimely death and the family conspiracy, the concubine Jiang Ning concealed the fact that she possessed peerless medical skills (poison skills) and entered the palace as a "sick beauty". Everyone in the harem thought that she would not survive that winter, so they despised and trampled on her. Who would have thought that she would use her body as bait, step by step, and turn her seemingly frail body into the sharpest weapon. Facing the Emperor Xiao Ce, who had a shady background, was suspicious by nature, and cruel in his methods, she did not talk about feelings but only interests. In the palace of intrigues, she not only defeated the domineering concubine and the scheming queen, but also gradually uncovered the shocking secrets of the royal bloodline, and finally took over the power and became the most powerful empress dowager in history.