Abandoned by her birth family for being a girl, Lin Zhiwan is cherished like a treasure by her adoptive parents. She studies all the way to a doctorate, only to lose her job after her boyfriend's childhood sweetheart frames her. She pours her savings into opening a huge pharmacy, but during a trip, an ancient totem tree cuts her. A blood-red flower appears on her shoulder, and it turns out to connect her to a palace a thousand years in the past.
The short-lived emperor on the other side is her childhood playmate, lost to her years ago. He once joined the army and rose to become a five-star general, but now his soul has crossed into another world, where he is trapped by imperial power. She wields modern medicine to help him secure his kingdom and bring peace to the realm. But when she travels to Myanmar to procure military supplies, she comes face-to-face with her biological older sister, who was abandoned just like her.
As the flower blooms and the ties between past and present grow ever deeper, what will happen when family bonds collide with political intrigue? Can she join hands with the emperor, turn the tide, and protect the people she loves?