In the eighth year of the Republic of China, Xiaohe, the five-year-old daughter of embroiderer Lin Wanniang, was misdiagnosed and died by Jia Renyi, a quack doctor at "Renxintang". Wan Niang complained but was framed and threw herself into the river in despair. Reborn at the bottom of the river and possessed by her soul, she became Shen Qingying, a female student of Western medicine who returned from studying abroad, and discovered that her original father was also killed by Jia's fake medicine. Two souls merge into one, a double blood feud. Qingying used the ambition of being "obsessed" to do justice: he pretended to be the daughter of a wealthy Nanyang businessman and approached Jia's family. He teamed up with Gu Qingshan, a businessman who takes both black and white, and Zhou Mingyuan, an upright reporter, to systematically collect evidence of crime. She used her knowledge of Western medicine to expose misdiagnosis in public, used emerging media to expose the "quackery serial murder case", and also exposed the Jia family's heinous crime of selling counterfeit medicines and opium and imprisoning the victims' families...