Gu Changfeng, a top student in the Department of Modern Forensic Medicine, accidentally traveled to the ancient Daqian Dynasty and was involved in a secret room murder case in which Li Jing, the prime minister's son, died mysteriously. Relying on his forensic knowledge and rigorous logic, he overturned the conclusion and exposed the treasonous conspiracy of the Eastern Palace Prince involved behind the case. From opening the coffin and discovering key evidence during the autopsy, to using fake account books to set up a trap to expose the prince's accomplices, Gu Changfeng worked among the prime ministers, generals and imperial power, gradually uncovering the prince's shocking conspiracy to collude with the Jurchen tribe and intend to subvert the kingdom.