Shen Qingli (the heroine), the saint of the demon sect, was betrayed by her fellow disciples, lost all her martial arts skills, was poisoned by a strange poison, and became a lost dog that everyone in the world wanted to beat. At the moment of life and death, she forcibly touches Xie Wuwang (the male protagonist), the legendary miracle doctor who "will not save anyone even in the face of death".
Relying on her extraordinary resourcefulness and ruthless methods, the heroine makes her way step by step in the Valley of Miracle Doctors. She must not only detoxify and restore her martial arts skills, but also deal with the encirclement and suppression of righteous people. The two used and tested each other, and then joined forces to abuse each other in the world. The female protagonist re-cultivates martial arts and develops peerless swordsmanship with a mortal body; the male protagonist uses medicine to enter martial arts, and the silver needle can save both people and ghosts.
In the end, the female protagonist uncovers a shocking conspiracy and takes control of the demon sect to clean up the family; the male protagonist breaks the "no-kill" oath for love, and the two strive to reach the top of the martial arts world, becoming the "Two Evils of Healing and Demons" who scare the world.