The heroine Shen Zhiwei traveled through time and became an unpopular concubine in the Prime Minister's Palace. Her biological mother died early and she was treated harshly by her mistress. On the surface, she is weak and tolerant, but in fact, she is secretly studying the art and medical theory of poisonous poison based on the "Secret Book of Poison Poison" left by her biological mother. The story begins when she is forced to marry a sick and cruel king of a different surname. She uses poison to control the king and uses medicine to seek power. From internal fighting in the palace to getting involved in party disputes in the court, she is involved in a series of whirlpools such as the prince's succession, border wars, and the secrets of the previous dynasty. Using poison as a blade and poison as a chess piece, she changed her fate against the will of the gods and revealed the mystery of her life experience (the legacy of the previous dynasty/the daughter of destiny). She finally broke away from the shackles, reached the pinnacle of power, and controlled the world with a like-minded male protagonist. The core excitement lies in "controlling violence with poison", "crushing with IQ", "counterattack and slap in the face" and "reaching the top of career".