She was originally the legitimate daughter of the general's palace, but she was considered unlucky because she was born with a poisonous body. She even had her fiancé break off the engagement in public on the day she was born! Once she awakens, she is no longer the submissive "trash", but the last descendant of the hidden Poison Doctor Valley - the "Poison Doctor Crazy Concubine" who is both skilled in medicine and poison! She used a bowl of poison to save the prince who was poisoned and whose life was hanging by a thread. However, she also got involved in the struggle for imperial power and the turmoil in the world. The fiancé regretted his mistake, but was poisoned by her to the point of crying for his father; the decent faction was afraid of her poisonous skills and wanted to take away her secret book; the evil faction wanted to win over her and help him seize power. What's even worse is that she discovered that the murderer of her master was inextricably linked to the royal family! Faced with the struggle of "should poison magic exist?", How can she use poison to control and balance, use medicine to save the world, and finally make the world surrender and change her destiny against nature?