In 2077 AD, the "Prometheus" virus, which aimed to rewrite human genes, went out of control and "optimized" most of the world's living organisms into horrific mutants. Mo Xiaoyao, a former genetic company researcher, witnessed his family members transform into mutants who retained some humanity but were trapped in monster bodies. With guilt for his family and obsession with finding an antidote, Mo Xiaoyao, who is strangely immune to the virus, leads the few remaining survivors in the apocalypse on an arduous journey to discover the truth about the virus and resolve the crisis of mutation. They must fight against the ever-evolving army of mutants in the wasteland and uncover the ultimate secret called the "Scarlet Code" hidden behind the virus.