The medical family was wiped out. The only surviving genius girl, Su Jinyan, disguised herself as a man and took the pseudonym "Su Jin" to avoid being hunted and seek revenge. With her martial arts and superb medical skills, she accidentally became the personal bodyguard of Xie Wujiu, the frail and imprisoned prince.
In the early days, the two tested each other. While Su Jinyan had to hide his identity as a woman and his hatred for the annihilation of his family, he had to deal with the many crises in the duke's palace, such as brothers killing each other and his stepmother supporting him. He also used medical skills to recuperate the body of the "sick son" and solve the poisoning conspiracy. Xie Wujiu, who seems gentle and harmless, has actually already understood her identity as a woman and secretly appreciates her tenacity and talent. He uses her protection to eliminate dissidents step by step.
In the middle period, the two established a solid trust and transformed from master and servant to inseparable comrades. The clues about Su Jinyan's enemies are intertwined with the struggle for the imperial throne. In order to protect her, Xie Wujiu no longer pretends to be sick and weak, but reveals his dark and cunning side. They join forces to deal with political opponents and put an end to the conspiracy. Su Jinyan's medical skills and resourcefulness become the greatest help to Xie Wujiu on his political strategy. Their relationship heats up rapidly during life and death, and they go in both directions.
Later, with the help of Xie Wujiu, Su Jinyan found out the truth behind the family's annihilation, killed his enemies, and avenged his injustice. She regained her identity as a woman and amazed the world. And Xie Wujiu also cleared all obstacles and gained power in both the government and the public. In the end, he took Jiangshan as his employer and married Su Jinyan as his queen. Together, they created a prosperous age of Haiyan and Heqing.