In three shocking cases spanning Chang'an, Lingnan, and Luoyang, Shen Qinghuan used medicine as an edge and wisdom to solve the problem, growing from a drug boy in a boudoir to a medical master protecting the common people. She got rid of the superstition of "poisonous evil spirits", exposed the shady story of "cold poison politics", and protected the people of the Tang Dynasty with professional knowledge and benevolence. "The Unexpected Cases of the Tang Dynasty" is not only a medical detective legend, but also a growth epic of a woman who sticks to her original aspirations and practices medicine in a patriarchal society.