Su Wan, a pharmacist who was born among the people, was forced to marry into the Liu Mansion, an aristocratic family on the verge of decline, to "bring happiness" to his legitimate son Yun Jing, who was terminally ill. Everyone was waiting for her, a cheap wife, to be buried as a widow, but they didn't expect her to take a potion and kill Yun Jing. In this prison where the wife is respected as the master, but the inner house is controlled by the ruthless "father-in-law" and various "side husbands", Su Wan uses medical skills as a sword and poisonous skills as a shield, and works every step of the way. She cured her husband, defeated the villain, reorganized the family business, and gradually pampered a sickly and beautiful husband into a "strict wife" that was envied by men all over the world. When all the conspiracy was revealed, she discovered that the husband she married was far more than a sickly beauty, and she herself had already transformed from a chess piece seeking survival to the world's best wife playing chess.