As the last disciple of the medical sage Li Shizhen, the protagonist Li Heqing shoulders the mission of completing the unfinished parts of the "Compendium of Materia Medica" after his master's death, and travels all over the mountains and rivers of the Ming Dynasty with the "Weiyang Volume" which records strange diseases and medicines. He used herbal medicine as a boat and medical skills as an oar. While healing flesh and blood, he experienced the dangers of the rivers and lakes, the treachery of the court, and the various aspects of human nature. He formed an indissoluble bond with the descendants of the Miao Gu doctors, and became friends and foes with the geniuses of the Taiyuan Hospital. In the end, he faced the powerful eunuchs who used medicine to bring harm to the government. He grew from a sincere young man who only knew the prescriptions to a generation of great doctors who truly understood what "the benevolence of a doctor" is and healed the wounds of the times.
