The story takes the main stage of an urban tertiary hospital. Lin Xiao has just been promoted to the attending doctor. The hospital is facing huge pressures such as expansion and influenza outbreak. Du Ruo's growth line, Song Wei's family line, Zhou Qiming's institutional line, and Mr. Zhang's life line are intertwined. Everyone is struggling in the trivial and high-pressure daily life. Crises occur frequently in the hospital, and everyone uses humor to laugh at themselves to relieve stress. They continue to break through themselves in the frontline of life and death, workplace maneuvering, friendship and love, experience misunderstanding, loss, redemption, reconciliation, and complete self-growth in laughter and tears. In the end, they protected the hospital in their own way and healed their own hearts.