The story takes place in a large tertiary hospital in the city center. The protagonists Tang Hao, Lin Shuang, Zhou Tong, Li You, Zhao Xue and Liu Fengchun each bear the responsibilities of different front-line medical positions. In the daily life where high pressure, triviality, and crises coexist, they face doctor-patient conflicts, major rescues, medical errors, and management reforms together. Through humorous daily chores, touching moments of crisis, and the intersection of family, friendship, love and self-salvation, the six people warmed each other and grew together. After several consecutive years of various incidents, the hospital has undergone tremendous changes. Team members have faced their personal difficulties and gained redemption and breakthroughs by accompanying each other. In the end, the protagonists used perseverance and courage to protect the temperature and bottom line of "Between White Clothes".