Su Jinli, the legitimate daughter of the prime minister's house, whose biological mother died young, was framed by her stepmother and concubine, and was given a marriage to the rumored disfigured and tyrannical King of Zhenbei. On their wedding night, she discovered that King Zhenbei had been poisoned by a strange poison, and she was the key to detoxifying it. It turns out that Su Jinli's biological mother was born in the mysterious Poison Valley in southern Xinjiang and left her a unique poison scripture. With her superb poison skills, she saved herself from the siege and formed a contractual alliance with King Zhenbei of "antidote in exchange for power". From then on, during the day she was a cowardly daughter who allowed others to bully her, and at night she was a poisonous doctor with the power of life and death. In the house fight, she made her stepmother and concubine suffer the consequences; in the palace fight, she helped Zhenbei King clear the obstacles; in the arena, she revived the reputation of Poison Valley. As she uncovered the truth about her biological mother's death step by step, she discovered that there was a shocking conspiracy to subvert the imperial power behind it. In the end, she used poison as a blade and medicine as a shield to avenge her mother with her own hands, trample all enemies under her feet, and join hands with her lover to reach the top of power.
