Li Qingwan, the top cardiac surgeon in modern times, was electrocuted at the peak of his operation, and his soul traveled through the Yin Dynasty to become a low-ranking "family son". When he first entered the palace, he was framed by Concubine Liu. After being scolded with a stick, he was bound to the "medical space" and thrown into the cold palace.
She rescued herself with space materials, made a "Snow Face Mask", and opened the black market with the help of the palace maid A Li and the eunuch Xiao Guizi, improving her life and coping with the imperial concubine's secret investigation. Emperor Xiao Jingheng was injured during a night patrol and accidentally ended up in the cold palace. Li Qingwan wore a veil and used modern medical techniques to sew him up, making the emperor worried.
Concubine Liu Guifei once again set up a trap to harm Li Qingwan, and the emperor appeared to protect her and promoted her to "Guiren Wan". In the harem, the queen and others set up witchcraft and false pregnancy schemes. Li Qingwan used modern medicine to break the situation and was awarded the title of "Medical Concubine", which caused controversy in the previous dynasty. After being poisoned, she saved herself. She was exhausted physically and mentally and wanted to return to the cold palace and have a cold war with the emperor.
"Red Rain Fever" broke out in the south of the Yangtze River. Li Qingwan asked for orders to go to the affected area, and the emperor went with him. She used artemisinin to save the people, and the emperor helped promote it, but the prime minister instigated another conflict. After the epidemic area was pacified, Li Qingwan was placed under house arrest. The emperor knelt down to watch the epiphany on a snowy night and set up the "Official Office of the Female Officials of the Taiyuan Hospital" to take charge of the hospital.
Later, Li Qingwan encouraged women to study medicine and marry the emperor. She donated medical supplies and wrote "Qingwan Medical Classic". Ten years later, medicine in Dayin flourished, and the emperor and his daughter opened a medical clinic for free. At the end, a scanned copy of "Qingwan Medical Classic" appeared in modern times, leaving a warm mark across time and space.