The story takes place in Guiyang, a city shrouded in "Dog God Qi Mou". The remains of the ancient dog gods (seven bronze pillars) are sealed underground, and there are 823,472 animals that were abandoned and turned into "shadow dogs" living on the ground. Xia Ning is the reincarnation of Xingxuan, the last priest of the Dog God Clan, and his body is filled with pure Yang blood that can activate the medicine beast. Tang Yuan is the seventh reincarnation of the God of War, Yaori Sirius, and has a seven-orificed exquisite heart that can heal all sentient beings. When the pure Yang blood is exhausted and the exquisite heart of the seven orifices closes, time begins to flow backwards. 823,472 Animals reversely grow into embryos, and the entire city faces the crisis of "returning to ruins". This is a Möbius strip-like story about the "seventh reincarnation" and the "eighth rebirth".