In the third year of Yongxi's reign, the Central Plains was ablaze with war, and Qingmang Mountain on the border became a safe haven in troubled times. In order to avoid family involvement, medical girl Shen Ningshuang hid in the mountains with her medicine box, but she rescued a man with strange injuries on a rainy night - Ye Canglan. His wounds healed quickly, his body temperature was different from normal people, and the sharp teeth and wolf ears that occasionally appeared in his coma allowed Shen Ningshuang to glimpse his unknown secrets.
Ye Canglan is actually a descendant of the wolf tribe in the north. He was hunted down due to civil strife in the tribe, and he has the mission of guarding the sacred relics of the wolf tribe. Shen Ningshuang's medical skills accidentally relieved the "Wolf Curse" in his body, and the two were forced to go together. On the way, they not only have to avoid the blade of the pursuer, but also have to deal with the covetousness of the Central Plains warlords, and they also have to face the barrier between humans and wolves. When Shen Ningshuang's old family case is intertwined with the secret of the wolf tribe's sacred relics, the love between the two gradually grows in the smoke of war, becoming the most fragile but also the most resilient light in troubled times. Can they break ethnic prejudices, protect each other in blood and fire, and uncover a greater conspiracy hidden behind the sacred objects?