Blind Zeng Xiaofan followed the widow Li Bixian to learn Chinese medicine to identify acupoints, but was harassed and provoked by the gangster Zhao Qinglong. In the chaos, Zeng Xiaofan suffered a head injury and unexpectedly awakened the inheritance of the "Heavenly Medical Ancestor". Not only did he regain his sight, he also gained peerless medical and martial arts skills. After that, he successively rescued the poisoned female star Li Bing and the kidnapped Li Bixian, exposed the corruption conspiracy of the village chief Jin Youcai, and led the villagers to get rich by using the "Tiandao Gourd" to ripen medicinal materials. During this period, he also foiled the tomb robbing and poisoning plots of the island country's forces, and gradually grew from a despised blind man to a miraculous doctor and warrior who protects his neighbors and possesses unique skills.
