Su Jin, the daughter of a convict from the Taiyuan Hospital, was imprisoned because of her father's murder, and was forced to enter the palace as a medical woman. She possesses the family's unique skill of "activating the golden needle" and the "clear eyes" power that can distinguish hundreds of poisons. She originally wanted to save her father by investigating the case, but she was repeatedly involved in the whirlpool of competition between concubines. From the chronic toxins in the concubine's anti-fetal medicine, to the hallucinogenic ingredients in the queen mother's decoction, to the panic caused by the strange illness of the female concubine, Su Jin used her medical skills to break the situation time and time again, and gradually attracted the attention of Emperor Xiao Jingyuan. She has to beware of the hypocritical schemes of the concubine Xian and the cruel schemes of the concubine Li, but also has to balance saving people and avoiding disaster. She also discovers that her father's injustice is closely related to the most powerful person in the harem. In the end, Su Jin used golden needles to treat emergencies and used prescriptions to prove her innocence. Not only did she overturn her father's case, she also used medical skills to establish the "Huimin Pharmacy" in the harem, so that the people at the bottom of the palace could be healthy and found a "medical harem path" that was different from other concubines.