In order to save her sick younger brother, Shen Qinghuan, a folk doctor, was forced to enter Prince Jing's Mansion to diagnose and treat the heart disease of the ascetic prince Xiao Jue, who was known as the "Living King of Hell". Xiao Jue is powerful but has an indifferent temperament. Due to childhood trauma and royal suspicion, he has long been isolated from the world with a frozen shell, and the Imperial Hospital is unable to do anything about his chronic illness.
When Shen Qinghuan first entered the palace, she was faced with cold words and alienation from daily life. However, she relied on her superb medical skills and sincerity to break the deadlock time and time again: calming acupuncture when an acute illness broke out, a warm-up medicine bag handed to her on a cold night, and a soothing medicinal meal that fit her heart, gradually melting away the prince's indifference. When her brother was framed, Xiao Jue, who had always ignored trivial matters, made an exception for a thorough investigation; when she was made things difficult for the powerful, he became angry and defended himself for the first time, declaring, "Who dares to touch my people?"
From testing and guarding to loving each other, from "it has nothing to do with me" to "I love you", the two of them stood side by side in the shadow of the court conspiracy and the past. In the end, Shen Qinghuan healed Xiao Jue's heart ailments and knots, and Xiao Jue cleared the obstacles for her. This fate that began with medical skills eventually turned into an exclusive and prosperous love for each other.