Jiang Yue, an elite special agent, was betrayed by her teammates during a mission. At a critical moment, she ignited explosives, and her soul transmigrated to ancient times, into the body of Su Wan. She unexpectedly met Jun Moli, and later learned that Jun Moli and his twin brother, Jun Moxie, both suffered from the congenital poison Purple Frost. To cure Jun Moli, Su Wan studied for five years in the Nine-Tier Trial Tower. Later, Jun Moli and Su Wan were married. Then the witch doctors of the Northern Qi Kingdom sought the brothers' blue blood to make an elixir of immortality, and war broke out. The witch doctors tried to capture the pregnant Su Wan, but she escaped. They then seized Jun Moxie and used him as a living blood source. Eventually, Su Wan and Jun Moli rescued him. Later, Su Wan and Bai Qinghe opened a medical clinic and saved many people, treating infertility, blindness, heart disease, appendicitis, and more. One great general was so grateful for being treated that he gave Su Wan a squad of soldiers. When Su Wan's son, Su Nian'an, was poisoned by the witch doctors, they discovered that the antidote required medicinal ingredients from the Upper Realm. Lei Lingzi helped contact allies there and obtain the ingredients for the antidote.
