On the border of southern Xinjiang, where poisons are rampant, a pharmacist girl, Xiao Qi, rescues the dying orphan A Chou from a mass grave. A Chou has a strange bloodline. His blood contains trace amounts of anti-toxic factors, but it is also full of highly toxic substances and is regarded as ominous by the world. In order to repay his life-saving grace, A Chou volunteered to become Xiao Qi's drug tester, testing the poison with his own body and helping him study the way to detoxify. Two marginalized souls expelled by fear and supercilious eyes depend on each other, trudging through a world full of thorns, just to find a "pure land" where A Chou can breathe and relieve the stubborn poison in his body. When the deadly plague comes, the ignorant villagers point their finger at the "poison-blooded" A Chou, forcing them to embark on a desperate road. During the escape, the poison accumulated in A Chou's body was on the verge of breaking out. Xiao Qi found the only solution in the ancient fragments, but he needed the medicine man's life as a guide. A Chou is willing to sacrifice, just to exchange for Xiao Qi's chance of survival. After nine days of refining the medicine, the fire in the furnace illuminates the farewell. When the medicine is ready and the furnace is opened, can the Pure Land really be found? On the balance of life and salvation, how will they choose?