During the Xuande period, strange things happened frequently in the capital. The owner of a silk and satin shop died mysteriously in his shop, with a strange bloody flower mark on his face. It was neither a stab wound nor a poison mark, making it an unsolvable mystery. Jinyiwei Xiaoqi Shen Yan seems to be a "social terrorist" migrant worker who is afraid of trouble, but in fact she has incredible observation skills and can find flaws from clues; Su Wan, the owner of the rouge shop "Wanxiang Pavilion", appears to be a pretty shopkeeper with makeup and powder, but secretly knows medicine and toxicology, and even the government has to respect her. The two collided due to the "Corpse Mask" case, one complained that it was troublesome, and the other refused to give up on getting to the bottom of it. They went from "enemies" who disliked each other to partners who joined forces to solve a series of mysteries. As the case progresses, they discover that the "Corpse Flower" is just the tip of the iceberg, and there are big secrets involving Jianghu forces and palace relics hidden behind it. The pasts of the two people are gradually becoming entangled with the case. In this investigation, not only must they find out the real murderer, but they must also deal with the "troublemaker" around them first!