Shen Qingwu, the legitimate daughter of the Shaoqing of Dali Temple, was executed by the whole family.
Living with a stigma attached to her, she unexpectedly discovers that the enemy who destroyed her family has skinned her entire family and made a set of "Seven Resentful Skin Drums" that can control people's hearts and confuse all living beings. In order to seek revenge and to find the "remains" of her family, Shen Qingwu transformed into a ghost-pen painter, tracing the bones with a brush to trace the truth. She relied on her extraordinary painting skills and photographic memory to fight for her death. In the process, she and Shi Xiexuan, the commander of the Wensheng Department who specializes in investigating mysterious cases, changed from old enemies who tested each other to allies who joined forces to break the situation, and jointly fought against the evil demon who used human skin as a musical instrument and ordinary people as sacrifices.