In 2025, a chain fission reaction occurred at the Donghai Nuclear Power Plant due to the invasion of a mysterious virus. The blue radiation cloud swept the world with cross-species mutated genes. Animals, insects and even humans mutated in the radiation: zombies lost their minds but gained super strength. Some infected people evolved intelligence and could even control mutated creatures to form legions. At the same time, astrophysicists discovered that the nuclear explosion accidentally opened a space rift, and that the screening mechanism of alien civilizations was hidden in the radiation cloud. Only civilizations that have passed "mutation evolution" can qualify for interstellar survival.
In this doomsday catastrophe, engineer Lin Shen, biologist Su Qing, and astrophysicist Chen Mo formed a core team to fight against zombies and extreme human forces while cracking the ultimate secret of radiation mutation. They gradually discovered that the source of all disasters actually pointed to mankind's obsession with "perfect genes", and the real salvation may lie in symbiosis with mutated creatures.