A modern forensic doctor traveled through time and became Meng Tianchu, a famous criminal master in Shuntian Prefecture of the Ming Dynasty, and took over the "case of the sudden death of the commander of the Jinyi Guards". He used autopsy techniques to find that the deceased died of chronic poisoning, and the clue pointed to Admiral Dongchang. Meng Tianchu worked around the Dongchang, Jinyiwei, and civil service groups, taking advantage of the "Beijing Prosecution" to bring down corrupt officials, but was involved in Prince Ning's rebellion. When he uncovered the evidence of rebellion, he discovered that the man behind the scenes was actually the great-uncle of the current emperor.