In order to save her seriously ill younger brother, Su Wantang, a victim from a poor family, sold herself and married into the prime minister's house to fill a house. Faced with the difficulties caused by her mother-in-law, the frame-up by her concubine, and the cold treatment of her husband Gu Zhao, she relied on her tenacity and self-taught medical skills to gain a foothold step by step, and even helped Gu Zhao solve troubles outside the court. When she thought she finally got Gu Zhao's true heart, she discovered that Gu Zhao's Bai Yueguang Shenmei was not dead, but was hidden away by Gu Zhao. After Shen Mei returned, she teamed up with her concubines to frame Su Wantang and even kidnapped her brother. Su Wantang was completely desperate and designed to expose Shen Mei's conspiracy, causing Gu Zhao to lose his position, the concubines to kill each other, and her mother-in-law to lose her power. In the end, Su Wantang left the Prime Minister's Mansion with his younger brother and children and started a new life. After losing everything, Gu Zhao discovered that what he really loved was Su Wantang, and he regretted it. When they reunited many years later, Su Wantang had already let go, and Gu Zhao spent the rest of his life making up for it.