Su Qingyuan, a modern chemical engineering PhD and heir to an ancient martial arts family, transmigrates to Qinglan Continent after a laboratory explosion. She becomes the good-for-nothing third young miss of the Su family in the Eastern Region, with blocked spiritual meridians. The moment she opens her eyes, her fiancé publicly breaks off their engagement, her half-sister humiliates her, and the truth behind her late mother's death remains shrouded in mystery.
At her lowest point, she awakens the Hongmeng Dimension, which contains a spiritual liquid extractor and ancient martial arts manuals. Using her modern chemistry knowledge to improve pills and combining ancient martial arts with spiritual techniques, she not only repairs her meridians but also awakens the rare dual attributes of lightning and space. She rises from an outcast of her family to become a legend of the Eastern Region.
Along the way, she meets the mysterious Mo Yuan, who appears to be a Spirit King realm traveler but is actually the young sect master of Tianyan Sect on Cangwu Continent, afflicted by a curse that devours spiritual energy. From cautiously joining forces to explore secret realms and seek a cure, to saving one another and uncovering their pasts, they learn that she is the reincarnation of a holy maiden of the Hongmeng Divine Clan, while he is descended from the Mo Clan's God of War, who once protected the Three Realms.
Across Qinglan, Cangwu, and Hongmeng, they seize divine seals, tame divine beasts, and battle demonic cultivators. Su Qingyuan stirs the world with her alchemy, artifact crafting, and formations, while Mo Yuan protects her with his weapon crafting and deadly arrays. When Demon Venerable Chonglou breaks free from his seal and seeks to destroy the Three Realms, this formidable couple leads the allied forces of all three realms to defend the seal and restore order, their defiant resolve setting the heavens ablaze. Together, they become legends who rule the Three Realms side by side.
