In Yingtian City during the Wanli Period of the Ming Dynasty, prosperity lurked beneath the surface. A series of bizarre murders were staged one after another. The deceased had a strange smile on his face, and there was no clue at the scene, making the people in the city panic. Shen Mo, the county government gangster who is careless but has amazing powers of observation, is forced to get involved in this mysterious case. While investigating the case, he met Su Qingyuan, a medical woman with superb medical skills and cold personality. One relies on street wisdom, and the other relies on professional medical skills to discern life and death. From the initial mutual quarrel to the tacit cooperation later, the two get closer to the truth step by step under layers of obstruction and dangerous threats. As the investigation deepened, they discovered that missing treasures and mysterious organizations from many years ago were involved behind these murders, and their pursuit also led to murders. When the truth gradually emerges, a huge conspiracy that can shake Yingtian City is also revealed. Can Shen Mo and Su Qingyuan bring the crime to justice before darkness falls?