During the Wanli period, strange things happened frequently in Pingjiang Mansion, a prosperous place in the south of the Yangtze River. A series of bizarre murders were exactly the same as the contents of the drama circulated in the market. Shen Mo, an unsuccessful scholar, has a lot of experience but fails in many trials. He makes a living by telling stories in teahouses, but he is accidentally involved in a "murder case predicted by plays." With his keen observation and logical thinking, he discovered that the case was full of doubts. At the same time, Su Qinghe, a folk doctor with a sassy personality and superb medical skills, met Shen Mo unexpectedly while performing an autopsy on a victim. One is good at finding clues from written details and human connections, and the other is good at discovering the truth from corpses and on-site evidence. From the initial suspicion of each other to the later tacit cooperation, the two work together to explore the truth. As the investigation deepened, they discovered that there was a larger conspiracy behind these cases, involving local officials, wealthy businessmen and even secret organizations. Every case is like a carefully choreographed drama. The murderer always seems to be unpredictable. In the process of chasing the murderer, Shen Mo and Su Qinghe not only have to face the dangerous case, but also deal with the obstruction and suppression from all sides. Can they uncover the truth amid the fog and allow justice to be served?