Shen Zhiwei, daughter of an imperial physician, escapes a family injustice by disguising herself as a man and practices medicine to help the people alongside her senior fellow apprentice, Lin Jingyun.
Xiao Heng, the general's son, is badly wounded and rescued by her, and feelings quietly grow between them. When her identity is exposed, Xiao Heng asks for her hand in marriage, but his proposal brings the truth behind a blood feud to light. Shen Zhiwei is devastated and leaves with Lin Jingyun for a distant land. Xiao Heng searches across the country for her and works to clear her family's name. When they meet again, a plague is raging, Lin Jingyun has turned dark, and love and hatred burn as they face a life-or-death choice.
The Shen family's downfall had another cause after all. Lin Jingyun deceived Shen Zhiwei and took her to a village in the southern frontier, using a love-control gu to claim her body and soul.
Xiao Heng uses his power to take Shen Zhiwei back. The two love and fight each other, but in the end their misunderstandings are resolved, and they spend their lives together.
