From 1925 to 1949, it spans three important historical periods: the Northern Expedition, the Anti-Japanese War, and the War of Liberation, and shows the ups and downs of the characters under the background of the great era. Through the marriage of a medical family and a shipping family, it shows the collision of Chinese and Western cultures, the entanglement of family and country feelings and personal emotions during the Republic of China, as well as the brilliance of human nature in troubled times.