"The Esoteric Empire" takes "cosmic symbiosis" as its core theme. It tells the story of a sci-fi epic in 2888 AD when the earth was mired in a resource civil war and a nuclear war was about to break out. Mi Fan, a scientist who had left the earth for 960 years and was already the founder of the Three Thousand Symbiosis Star Field, returned to his homeland with his silicon-based carbon-based composite assistant Shu Meili on Mi Wang 1. The work adopts a dual-line narrative of the earth and the interstellar world. Mi Fan uses the final seventh area of the Devil's Forest as his base, and joins forces with peaceful forces such as Chen Lao and Lin Ye to improve the lunar soil and build a new lunar home while fighting Zhao Tianxiong, the leader of the main war faction who colludes with the predators. At the same time, the leader of the predators, Xue Sha, takes advantage of Mi Fan's departure to launch a massive attack on the symbiosis star field. The old consul of Xingyuan leads the people to resist, and Mi Fan is forced to fight on two fronts. As the war situation escalated, Mi Fan discovered that the Blood Evil planned to use the earth as a springboard to devour the symbiotic star field, so he introduced symbiotic patterns to the earth to promote the establishment of a connection between humans and symbiotic civilization. In the end, Mi Fan led the coalition of humans and symbiotic civilizations on earth to completely defeat the predators, crush Zhao Tianxiong's dictatorial ambitions, and eliminate the crisis of nuclear war on earth. The earth's civilization has officially integrated into the symbiotic era. Mi Fan promotes all races to build a symbiotic order in the universe, and eventually leads the younger generation to explore the super-dimensional space, allowing the concept of symbiosis to continue in the broader universe, interpreting the core theme of "symbiosis is the ultimate law for the survival of civilization."