On a stormy night, wealthy businessman Zhao Hongyuan is found dead under mysterious circumstances in his locked study. Half a glass of poisoned wine and blurred fingerprints conceal murderous intent, while his wife Zhou Hui's lies and the cuts on her wrist deepen the suspicions.
Veteran detective Zhang Cheng and rookie Lin Wei investigate. The vice president Gao Ming's gap in the surveillance footage, the private doctor Chen Bin's mysterious whereabouts, and a smuggling network exposed by an anonymous tip lead the case into an even deeper whirlpool.
As customs officer Liu Zhijun is found brutally murdered and chief Li Jianguo lets his guard slip, the truth behind the locked-room mystery begins to emerge. Yet just as the case is solved, a new one comes to light: a female college student with a white rose through her chest, killed using the same method as an unsolved case from three years ago! Retired Doctor Wang surfaces, and the symbols on his prescription slip match traces found on the USB drive from Zhao Hongyuan's case. The vast criminal web behind both cases has only just begun to reveal itself...