After her family falsely accuses her, Su Qingci, daughter of the Imperial Medical Academy’s director, goes into hiding in Jiangnan and practices medicine. There she meets Prince Jing, Xiao Jue, who has been injured while investigating a case. From testing one another to joining forces, the two uncover the old case against the Su family and the political machinations at court. Through misunderstandings and ordeals that test them to the brink of death, their love deepens and they pledge themselves to each other. In the end, the Su family is exonerated, and the couple marry in a flourishing age. Together, they defend the borderlands and advance the medical profession, forging a historical romance of mutual devotion and shared duty to their country.