A plane crash leaves financial elite Xu Ming and head nurse Zhou Lan stranded on a desert island. Facing an existential crisis, the two transformed from stranger neighbors into life-or-death partners. When the World War II biological experiments and poaching gangs hidden on the island surface, they must work together to fight against the evils of nature and human nature. In an extreme environment, Xu Ming learned to let go of his elite arrogance, and Zhou Lan regained his courage. When they were finally rescued, they brought back not only scars, but also souls reshaped by the desert island.