Shen Qinghe, the daughter of the imperial physician Ling, was killed in a well-planned poison case at a palace banquet. In order to find out the truth, she changed her name to "Ho Lu" and infiltrated the strict palace as a humble medical girl. Relying on her family's unique knowledge and extraordinary courage, she cured noble people, cracked strange poisons, dealt with the open and secret attacks of Shang Yao Bureau, and formed a life-or-death alliance with the prince Zhao Yanqing who was in the whirlpool of power.
From the palace to the plague battlefield in the north, Shen Qinghe gradually discovered that his father's injustice was just the tip of the iceberg. A huge conspiracy network with poison as the blade and corruption as the chain, pointing directly at the country's foundation, gradually emerged. The mastermind behind the scenes has all the power and cruel methods, and even extends his poisonous hand to the Ninth Five-Year Plan.
Above the Golden Palace, facing a powerful enemy's frame-up and numerous murderous intentions, Shen Qinghe held the certificate alone, using the benevolence of a doctor as his armor and the mountain of iron-clad evidence as his blade, he uncovered the truth intertwined with blood and tears amidst the thunder in the court hall. On the day when her injustice was overturned, she refused to live in the temple, and chose to use the golden needle in her hand to open a medical school, spreading the "Splendid Medical Heart" to the world, and composing a legend of saving the world beyond love, hatred and hatred in the mountains and rivers.