Shen Shuyan, a modern medical student, travels back to the Zhenguan period of the Tang Dynasty in an accident. When he first arrived, he rescued an injured old man in a ruined temple and went to Chang'an with the refugees. However, because the porridge soup was suspended, he treated diseases in a medical shack outside the city, which made him jealous of the local medical clinic.
During the treatment, Shen Shuyan accidentally activated the mysterious mutton-fat jade pendant and found that it could help wound healing and enhance the efficacy of medicine. With the help of modern medical skills and jade pendant, he successfully cured Qin Qiong's knife injury and became famous. He was regarded as a guest of honor by the Duke Protector's Palace.
Soon, Queen Changsun became seriously ill, and the doctors were at a loss. Shen Shuyan was summoned to the palace and was diagnosed with an emergency, so he was cured using modern surgery combined with traditional Chinese medicine. Li Shimin was overjoyed and made him a palace medical officer and gave him a mansion.
However, Shen Shuyan was involved in a palace struggle and was accused of poisoning the prince. He used the power of the jade pendant and medical knowledge to uncover the real culprit and clear his grievances.
In order to explore the secret of the jade pendant, Shen Shuyan embarked on a journey to Zhongnan Mountain. Along the way, he treated diseases and saved people, met strange people and strangers, and got involved in disputes in the Jianghu. Let's see how he wrote legendary medicine in the Tang Dynasty.