Biologist Su Rui accidentally gained the ability to become immortal in a laboratory explosion in 2045, and began an eighty-year wandering of loneliness. She kept changing identities, watching the people she loved grow old and die one by one, and witnessed the rise and fall of human civilization and the cycle of war, until she met Lin Mo, a time traveler who claimed to be from 2389, at an Antarctic research station in 2125.
Lin Mo told her a cruel future: mankind is on the verge of extinction due to a genetic virus called "Blight", and her serum is the only antidote. But historical records show that she would die three days later.
In order to save the future, Su Rui followed Lin Mo through time and space, only to find that the world in 2389 was far darker than imagined - the oceans dried up, cities were in ruins, and the mysterious "New Eden Project" was trying to use her immortal genes to create so-called "perfect humans." What shocked her even more was that Lin Mo was no ordinary space-time agent. He had an unexplainable genetic resonance with her serum, and there was a mysterious connection between the two that transcended time and space.
In this escape across time, Su Rui must face an ultimate choice: Sacrifice herself to save mankind, or break fate and continue to live forever?