Huo Chenxiao, a retired iron-blooded escort leader from the frontier fortress, lived in the south of the Yangtze River with his three-year-old son Huo Azhao. Because the child was born with abnormal pupils, charlatans spread the prophecy of "blood pupils destroying the world" and were hunted down by many parties. When he was desperate, he met the reclusive genius doctor Xue Lingzhao. In order to find out the truth of the prophecy and protect A-Zhao, the two got involved in an old case of a traitor from the medical sect colluding with a cult twenty years ago. Xue Lingzhao used his exquisite medical skills to solve the serial drug saga, and Huo Chenxiao used his iron-blooded methods to tear apart the web of conspiracy. In the daily life of raising Azhao, he gradually became emotional, and finally revealed that the prophecy was a forgery, and the villain used the name of "destroying the world" to usurp the medical practice.
