Du Qingtang, the legitimate daughter of the Minister of Rites of the Zhou Dynasty, learned superb medical skills from her grandfather, an imperial physician, since she was a child. However, she was forced by her stepmother to get married many times. While escaping from marriage, she mistakenly entered the Zen monastery where the prince of Jingyuan, Mo Yunyuan, was recovering from his injuries. She used her medical skills to gain insight into his old injuries, and the two of them had a startling glimpse. A strange disease breaks out in the capital. Du Qingtang takes a risk to rescue her but is blocked by her stepmother. Mo Yunyuan invites her to help treat the epidemic in the name of the Marquis Mansion. The two gradually develop a love for each other during the treatment. When the border is in danger and Mo Yunyuan is ordered to go on an expedition, bad news suddenly comes. Du Qingtang disguises herself as a man and travels thousands of miles to find her husband. With her medical skills and wisdom, she not only rescues the seriously injured prince, but also exposes the conspiracy of the DPRK and China to collude with foreign enemies. From the scent of medicine in the Zen monastery where they first met to the border of life and death, a generation of medical women and generals, the god of war, compose a beautiful marriage that transcends family backgrounds and helps the world together through their machinations and true love.