Xie Chang'an, a framer from the Republic of China, took over the handed down ancient painting "Nine Beauties" and discovered that the beauties in the painting changed their postures every day, and modifying the picture actually caused changes in reality. As the investigation deepens, she uncovers a horrific sacrificial tradition that has lasted for hundreds of years—each generation needs to sacrifice a framer to seal it in the painting. When the cinnabar mole on Xie Changan's wrist turned into the same rouge color as when Shen Zhiwei committed suicide, she was shocked to realize that she was the 100th sacrifice. With the help of Gu Qingzhou and the painting slave, she used the wedding silk thread to embroider the beauty's face, and finally broke the situation by burning the painting, but found a deeper conspiracy in the newly born "Ten Beautiful Pictures"