Su Chenbi, an orphan from the Medicine Valley, was hunted down by the Immortal Sect due to his "evil body" constitution. He escaped in a desperate situation by relying on his unique skills in medicine and poisoning, and accidentally got involved in the ancient secrets of the "Battle to Overcome Calamity Thousands of Years Ago". From being a "catastrophe star" hunted by all forces, she gradually uncovered the truth about her bloodline and "evil body" - the so-called "evil body" is actually the inheritance of ancient people who survived adversity, and she needs to use medicine and poison to resolve the disasters in the world. In the process, she outsmarted the Immortal Sect's conspiracy, rescued endangered monks, and cracked the ancient poison array. Finally, she rebuilt the monument to overcome disasters in a mortal body and became the "Emissary of disasters" that awes all races. The highlights are the highlight moments of counter-attacking in desperate situations, breaking through poisonous medicine, and reversing her identity.