Yunnan Xing, a young lead dancer, is introduced by her mother to Ma Yanchen, a brilliant doctor at a neurological research institute. Since they are both at the age to marry, they tie the knot in a whirlwind wedding. After all kinds of trials, they go from strangers to confidants, and then slowly fall for each other. Just as their feelings reach their most tender and uncertain point, Yunnan Xing is diagnosed with brain cancer. Ma Yanchen stays by her side and even tries to use his position to find a way to save her. But fate is cruel: her illness cannot be treated. The two spend their time together fulfilling her final three wishes… Many years later, after developing a special treatment for the same illness that took his wife, Ma Yanchen follows the setting sun…