The medical saint princess of Xizhao is married off to the Third Prince of Dayin. They fall in love, and she helps him ascend the throne. She thinks they have reached a happy ending, but then discovers that her beloved was responsible for destroying her homeland. Their love turns into a blade. She fakes her death to escape, is reborn on the grasslands, and returns with ingenious plans drawn from the world of plants. Once lovers, now enemies, can she use her medical skills to turn the world upside down and make the emperor regret his ruthless deeds?