In the 21st century, Chen Shaoyou (24 years old), a graduate student at the University of Traditional Chinese Medicine, died in a car accident, and his soul passed through the body of a beggar in Yangzhou City in the late Sui Dynasty (a parallel world in The Legend of Double Dragons of the Tang Dynasty). At this time, it was the seventh year of the Great Cause (611), and the world was about to be in chaos. Gao Zhong and Xu Ziling first emerged from the Jianghu, and forces such as Wang Shichong, Li Mi, and Dou Jiande were secretly surging. Yangzhou, as a hub between the north and the south, hid the struggle between all parties. Chen Shaoyou relied on his knowledge of modern Chinese medicine, historical predictions and Machiavellian thinking to rise from the bottom and rewrite the chaotic times of the late Sui Dynasty.